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To determine whether the improved PK properties of the QMP-engineered fusions would translate into enhanced efficacy, we repeated the GTT in human FcRn Tg32 mice

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However, it may be important to note that the main producers of TGF-1 in the adult hippocampus are glia and immune cells, while our data demonstrate that GDF11 is primarily produced by neuronal and oligodendrocyte-lineage cells [23, 24]